Drug interactions
Captopril-hydrochlorothiazide + Rose hips
Severity: Minor
Captopril-hydrochlorothiazide and Rose hips: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rose hips contain vitamin C and organic acids, and a theoretical competition for renal tubular secretion with hydrochlorothiazide has been proposed. No meaningful clinical effect has been demonstrated.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Rose hips have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical competition for organic anion tubular secretion in the kidney.
What to do
No action is generally required beyond routine blood pressure monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Rose hips?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Rose hips have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rose hips contain vitamin C and organic acids, and a theoretical competition for renal tubular secretion with hydrochlorothiazide has been proposed. No meaningful clinical effect has been demonstrated.
How serious is the interaction between Captopril-hydrochlorothiazide and Rose hips?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally required beyond routine blood pressure monitoring.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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