Drug interactions
Carbenoxolone + Formoterol-mometasone
Severity: Moderate
Carbenoxolone and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbenoxolone has mineralocorticoid-like activity that causes potassium loss and sodium retention. Formoterol shifts potassium into cells, and inhaled corticosteroids may contribute slightly. Together they can lead to clinically relevant hypokalemia, raising arrhythmia risk.
What this interaction means in plain words
Carbenoxolone and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from renal potassium wasting (carbenoxolone) and beta-2 mediated intracellular potassium shift (formoterol).
What to do
Monitor serum potassium periodically and replace potassium as needed. Take extra care in patients with heart disease or on other potassium-lowering drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Carbenoxolone with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Carbenoxolone and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbenoxolone has mineralocorticoid-like activity that causes potassium loss and sodium retention. Formoterol shifts potassium into cells, and inhaled corticosteroids may contribute slightly. Together they can lead to clinically relevant hypokalemia, raising arrhythmia risk.
How serious is the interaction between Carbenoxolone and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium periodically and replace potassium as needed. Take extra care in patients with heart disease or on other potassium-lowering drugs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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