Drug interactions
Carbenoxolone + Isoproterenol
Severity: Moderate
Carbenoxolone and Isoproterenol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbenoxolone has mineralocorticoid-like activity that causes potassium loss, and isoproterenol can further lower serum potassium. Hypokalemia may raise the risk of arrhythmias.
What this interaction means in plain words
Carbenoxolone and Isoproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from renal potassium wasting (carbenoxolone) and beta-2 mediated cellular potassium uptake.
What to do
Monitor serum potassium and replace as needed. Monitor ECG in patients with cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Carbenoxolone and Isoproterenol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Isoproterenol
Frequently asked questions
Can I take Carbenoxolone with Isoproterenol?
MediHelp rates the interaction as moderate. Carbenoxolone and Isoproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbenoxolone has mineralocorticoid-like activity that causes potassium loss, and isoproterenol can further lower serum potassium. Hypokalemia may raise the risk of arrhythmias.
How serious is the interaction between Carbenoxolone and Isoproterenol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace as needed. Monitor ECG in patients with cardiac disease.
What other medicines interact with Isoproterenol?
MediHelp also lists interactions of Isoproterenol with, for example, Adrenaline-articaine, Bisoprolol, Budesonide-formoterol. The full list is on the Isoproterenol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
