Drug interactions
Carbinoxamine + Gabapentin
Severity: Moderate
Carbinoxamine and Gabapentin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carbinoxamine is a sedating antihistamine and gabapentin also causes drowsiness. Together they can increase sedation and psychomotor impairment.
What this interaction means in plain words
Carbinoxamine and Gabapentin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbinoxamine belongs to Respiratory; Gabapentin belongs to Central Nervous System.
Why it happens
Additive central nervous system depression.
What to do
Monitor for excessive sedation and dizziness and use the lowest effective doses. Advise patients against driving until the response is known.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gabapentin
Other interactions of Carbinoxamine
- Alprazolam + Carbinoxamine Moderate
- Amisulpride + Carbinoxamine Moderate
- Amitriptyline + Carbinoxamine Moderate
- Amobarbital + Carbinoxamine Moderate
- Asenapine + Carbinoxamine Moderate
- Azelastine-fluticasone + Carbinoxamine Moderate
Frequently asked questions
Can I take Carbinoxamine with Gabapentin?
MediHelp rates the interaction as moderate. Carbinoxamine and Gabapentin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbinoxamine is a sedating antihistamine and gabapentin also causes drowsiness. Together they can increase sedation and psychomotor impairment.
How serious is the interaction between Carbinoxamine and Gabapentin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and dizziness and use the lowest effective doses. Advise patients against driving until the response is known.
What other medicines interact with Gabapentin?
MediHelp also lists interactions of Gabapentin with, for example, Alprazolam, Amobarbital, Belladonna and opium. The full list is on the Gabapentin page.
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