Drug interactions
Carbonyl iron + Ibandronate
Severity: Moderate
Carbonyl iron and Ibandronate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron binds oral ibandronate in the gut and reduces its absorption. This can lower the efficacy of ibandronate.
What this interaction means in plain words
Carbonyl iron and Ibandronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Ibandronate belongs to Musculoskeletal.
Why it happens
Chelation of ibandronate by polyvalent iron cations in the gastrointestinal tract.
What to do
Take ibandronate on an empty stomach with plain water and wait at least 60 minutes before iron or food. Consider IV ibandronate if separation is not practical.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ibandronate
- Aluminum hydroxide + Ibandronate Moderate
- Calcium acetate + Ibandronate Moderate
- Calcium carbonate + Ibandronate Moderate
- Calcium chloride + Ibandronate Moderate
- Calcium citrate + Ibandronate Moderate
- Calcium gluconate + Ibandronate Moderate
Other interactions of Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Calcium acetate + Carbonyl iron Moderate
- Calcium carbonate + Carbonyl iron Moderate
- Calcium + Carbonyl iron Moderate
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderate
Frequently asked questions
Can I take Carbonyl iron with Ibandronate?
MediHelp rates the interaction as moderate. Carbonyl iron and Ibandronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron binds oral ibandronate in the gut and reduces its absorption. This can lower the efficacy of ibandronate.
How serious is the interaction between Carbonyl iron and Ibandronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take ibandronate on an empty stomach with plain water and wait at least 60 minutes before iron or food. Consider IV ibandronate if separation is not practical.
What other medicines interact with Ibandronate?
MediHelp also lists interactions of Ibandronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ibandronate page.
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