Drug interactions
Carmustine + Vitamin e
Severity: Minor
Carmustine and Vitamin e: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antioxidants such as vitamin E are theorized to interfere with the oxidative damage that contributes to the cytotoxicity of alkylating agents like carmustine. This could reduce antitumor efficacy, but clinical evidence is lacking.
What this interaction means in plain words
Carmustine and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carmustine belongs to Oncology; Vitamin e belongs to Gastrointestinal Tract.
Why it happens
Theoretical antioxidant scavenging of reactive species involved in the cytotoxic action of carmustine.
What to do
Avoid high-dose antioxidant supplements during chemotherapy unless the oncology team agrees. Review all supplement use at treatment planning.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vitamin e
- Betrixaban + Vitamin e Moderate
- Phenindione + Vitamin e Moderate
- Selumetinib + Vitamin e Moderate
- Vitamin e + Warfarin Moderate
- Alfalfa + Vitamin e Minor
- Antithrombin alfa + Vitamin e Minor
Other interactions of Carmustine
- Carmustine + Pentostatin Contraindicated
- Carmustine + Chlorambucil Major
- Carmustine + Cimetidine Major
- Carmustine + Cyclophosphamide Major
- Carmustine + Dacarbazine Major
- Carmustine + Fingolimod Major
Frequently asked questions
Can I take Carmustine with Vitamin e?
MediHelp rates the interaction as minor. Carmustine and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antioxidants such as vitamin E are theorized to interfere with the oxidative damage that contributes to the cytotoxicity of alkylating agents like carmustine. This could reduce antitumor efficacy, but clinical evidence is lacking.
How serious is the interaction between Carmustine and Vitamin e?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid high-dose antioxidant supplements during chemotherapy unless the oncology team agrees. Review all supplement use at treatment planning.
What other medicines interact with Vitamin e?
MediHelp also lists interactions of Vitamin e with, for example, Betrixaban, Phenindione, Selumetinib. The full list is on the Vitamin e page.
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