Drug interactions
Carvedilol + Treprostinil
Severity: Moderate
Carvedilol and Treprostinil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a prostacyclin analogue with potent vasodilating properties. Combined with carvedilol, it may cause additive hypotension.
What this interaction means in plain words
Carvedilol and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carvedilol belongs to Cardiovascular; Treprostinil belongs to Cardiovascular.
Why it happens
Additive vasodilation and blood pressure lowering.
What to do
Monitor blood pressure and symptoms of hypotension when starting or adjusting treprostinil, and reduce the antihypertensive dose if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carvedilol
Other interactions of Treprostinil
Frequently asked questions
Can I take Carvedilol with Treprostinil?
MediHelp rates the interaction as moderate. Carvedilol and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Treprostinil is a prostacyclin analogue with potent vasodilating properties. Combined with carvedilol, it may cause additive hypotension.
How serious is the interaction between Carvedilol and Treprostinil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and symptoms of hypotension when starting or adjusting treprostinil, and reduce the antihypertensive dose if needed.
What other medicines interact with Carvedilol?
MediHelp also lists interactions of Carvedilol with, for example, Amifostine, Amiodarone, Arformoterol. The full list is on the Carvedilol page.
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