Drug interactions
Cefadroxil + Meclofenamic acid
Severity: Minor
Cefadroxil and Meclofenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefadroxil is secreted by renal tubular organic anion transporters and could slightly reduce the elimination of meclofenamic acid. The clinical effect is expected to be small.
What this interaction means in plain words
Cefadroxil and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefadroxil belongs to Anti Bacterial; Meclofenamic acid belongs to Musculoskeletal.
Why it happens
Competition for renal tubular secretion via organic anion transporters.
What to do
No routine action needed; watch for increased NSAID adverse effects such as GI upset in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Frequently asked questions
Can I take Cefadroxil with Meclofenamic acid?
MediHelp rates the interaction as minor. Cefadroxil and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefadroxil is secreted by renal tubular organic anion transporters and could slightly reduce the elimination of meclofenamic acid. The clinical effect is expected to be small.
How serious is the interaction between Cefadroxil and Meclofenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action needed; watch for increased NSAID adverse effects such as GI upset in patients with renal impairment.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
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