Drug interactions
Cefprozil + Neomycin po
Severity: Minor
Cefprozil and Neomycin po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cephalosporins have been reported to add to aminoglycoside nephrotoxicity. Oral neomycin is poorly absorbed, so systemic exposure is small unless there is impaired gut mucosa or renal impairment, which makes a significant interaction unlikely.
What this interaction means in plain words
Cefprozil and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive nephrotoxicity; oral neomycin has minimal systemic absorption.
What to do
Monitor serum creatinine in patients with renal impairment or inflamed bowel. Otherwise no change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefprozil
- Amikacin + Cefprozil Moderate
- Bcg vaccine live + Cefprozil Moderate
- Cefprozil + Cholera vaccine Moderate
- Cefprozil + Gentamicin Moderate
- Cefprozil + Microbiota Moderate
- Cefprozil + Plazomicin Moderate
Frequently asked questions
Can I take Cefprozil with Neomycin po?
MediHelp rates the interaction as minor. Cefprozil and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cephalosporins have been reported to add to aminoglycoside nephrotoxicity. Oral neomycin is poorly absorbed, so systemic exposure is small unless there is impaired gut mucosa or renal impairment, which makes a significant interaction unlikely.
How serious is the interaction between Cefprozil and Neomycin po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine in patients with renal impairment or inflamed bowel. Otherwise no change is needed.
What other medicines interact with Cefprozil?
MediHelp also lists interactions of Cefprozil with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefprozil page.
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