Drug interactions
Cefprozil + Plazomicin
Severity: Moderate
Cefprozil and Plazomicin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and cephalosporins have been reported to add to renal injury in some settings. Cefprozil itself is only weakly nephrotoxic, so the added risk is modest but relevant in patients with existing kidney impairment.
What this interaction means in plain words
Cefprozil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefprozil belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Why it happens
Possible additive nephrotoxicity of cephalosporin with aminoglycoside.
What to do
Monitor serum creatinine and plazomicin concentrations during therapy. Adjust the plazomicin dose to renal function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cefprozil
- Amikacin + Cefprozil Moderate
- Bcg vaccine live + Cefprozil Moderate
- Cefprozil + Cholera vaccine Moderate
- Cefprozil + Gentamicin Moderate
- Cefprozil + Microbiota Moderate
- Cefprozil + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderate
Other interactions of Plazomicin
- Cefaclor + Plazomicin Moderate
- Cefadroxil + Plazomicin Moderate
- Cefalexin + Plazomicin Moderate
- Cefazolin + Plazomicin Moderate
- Cefditoren + Plazomicin Moderate
- Cefepime + Plazomicin Moderate
Frequently asked questions
Can I take Cefprozil with Plazomicin?
MediHelp rates the interaction as moderate. Cefprozil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and cephalosporins have been reported to add to renal injury in some settings. Cefprozil itself is only weakly nephrotoxic, so the added risk is modest but relevant in patients with existing kidney impairment.
How serious is the interaction between Cefprozil and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during therapy. Adjust the plazomicin dose to renal function.
What other medicines interact with Cefprozil?
MediHelp also lists interactions of Cefprozil with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefprozil page.
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