Drug interactions
Cefprozil + Temocillin
Severity: Minor
Cefprozil and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are beta-lactams eliminated by renal tubular secretion, so they may compete for secretion and modestly raise each other's levels. This is rarely clinically significant given their wide therapeutic margins, though it matters more in renal impairment.
What this interaction means in plain words
Cefprozil and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal tubular secretion.
What to do
No routine adjustment is needed. Check renal function and dose to creatinine clearance in renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefprozil
- Amikacin + Cefprozil Moderate
- Bcg vaccine live + Cefprozil Moderate
- Cefprozil + Cholera vaccine Moderate
- Cefprozil + Gentamicin Moderate
- Cefprozil + Microbiota Moderate
- Cefprozil + Plazomicin Moderate
Frequently asked questions
Can I take Cefprozil with Temocillin?
MediHelp rates the interaction as minor. Cefprozil and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are beta-lactams eliminated by renal tubular secretion, so they may compete for secretion and modestly raise each other's levels. This is rarely clinically significant given their wide therapeutic margins, though it matters more in renal impairment.
How serious is the interaction between Cefprozil and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Check renal function and dose to creatinine clearance in renal impairment.
What other medicines interact with Cefprozil?
MediHelp also lists interactions of Cefprozil with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefprozil page.
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