Drug interactions
Celecoxib + Devil's claw
Severity: Minor
Celecoxib and Devil's claw: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw is used for joint pain and has reported antiplatelet activity and occasional bleeding reports. Taken with celecoxib it may add to bleeding or gastrointestinal irritation, but evidence is weak.
What this interaction means in plain words
Celecoxib and Devil's claw have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; mechanism is not well established.
What to do
Counsel patients to report bleeding or black stools. Avoid the combination when other antithrombotic drugs are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Devil's claw?
MediHelp rates the interaction as minor. Celecoxib and Devil's claw have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw is used for joint pain and has reported antiplatelet activity and occasional bleeding reports. Taken with celecoxib it may add to bleeding or gastrointestinal irritation, but evidence is weak.
How serious is the interaction between Celecoxib and Devil's claw?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report bleeding or black stools. Avoid the combination when other antithrombotic drugs are used.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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