Drug interactions
Celecoxib + Dexfenfluramine
Severity: Minor
Celecoxib and Dexfenfluramine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celecoxib is a moderate CYP2D6 inhibitor and may raise levels of CYP2D6 substrates. Dexfenfluramine has been withdrawn from the market, so the interaction has little current practical relevance.
What this interaction means in plain words
Celecoxib and Dexfenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Celecoxib inhibition of CYP2D6 may reduce dexfenfluramine metabolism.
What to do
Dexfenfluramine is no longer marketed. If encountered, monitor for increased serotonergic or adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Dexfenfluramine?
MediHelp rates the interaction as minor. Celecoxib and Dexfenfluramine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Celecoxib is a moderate CYP2D6 inhibitor and may raise levels of CYP2D6 substrates. Dexfenfluramine has been withdrawn from the market, so the interaction has little current practical relevance.
How serious is the interaction between Celecoxib and Dexfenfluramine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Dexfenfluramine is no longer marketed. If encountered, monitor for increased serotonergic or adverse effects.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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