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Drug interactions

Celecoxib + Dong quai

Severity: Minor

Celecoxib and Dong quai: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Dong quai contains coumarin-type constituents and has been associated with increased INR and bleeding. With celecoxib, bleeding risk may be modestly additive, though documentation is limited.

What this interaction means in plain words

Celecoxib and Dong quai have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive effects on hemostasis from coumarin derivatives and NSAID-related mucosal injury.

What to do

Advise avoiding dong quai while on celecoxib, particularly with other anticoagulants. Monitor for bruising or bleeding if used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Celecoxib with Dong quai?

MediHelp rates the interaction as minor. Celecoxib and Dong quai have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dong quai contains coumarin-type constituents and has been associated with increased INR and bleeding. With celecoxib, bleeding risk may be modestly additive, though documentation is limited.

How serious is the interaction between Celecoxib and Dong quai?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding dong quai while on celecoxib, particularly with other anticoagulants. Monitor for bruising or bleeding if used.

What other medicines interact with Celecoxib?

MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.

Full monographs, dosing and an interaction checker in the MediHelp app

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