Drug interactions
Celecoxib + Ganciclovir
Severity: Minor
Celecoxib and Ganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are renally handled and celecoxib could theoretically compete for tubular secretion of ganciclovir. NSAIDs may also reduce renal perfusion, which could raise ganciclovir exposure in patients with renal compromise.
What this interaction means in plain words
Celecoxib and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Ganciclovir belongs to Anti Virals.
Why it happens
Possible competition for renal tubular secretion and NSAID-related reduction in renal blood flow.
What to do
Monitor renal function and adjust ganciclovir dose to creatinine clearance, watching for hematologic toxicity.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Ganciclovir
Frequently asked questions
Can I take Celecoxib with Ganciclovir?
MediHelp rates the interaction as minor. Celecoxib and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are renally handled and celecoxib could theoretically compete for tubular secretion of ganciclovir. NSAIDs may also reduce renal perfusion, which could raise ganciclovir exposure in patients with renal compromise.
How serious is the interaction between Celecoxib and Ganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and adjust ganciclovir dose to creatinine clearance, watching for hematologic toxicity.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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