Drug interactions
Celecoxib + Ginger
Severity: Minor
Celecoxib and Ginger: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginger may inhibit platelet aggregation at higher supplemental doses, which could theoretically add to NSAID-related bleeding. Evidence for clinically meaningful bleeding is weak.
What this interaction means in plain words
Celecoxib and Ginger have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Ginger belongs to Gastrointestinal Tract.
Why it happens
Possible thromboxane synthesis inhibition by ginger constituents adding to NSAID effects; not firmly established.
What to do
No routine change is needed; advise reporting bruising or bleeding, and avoid high-dose ginger supplements around surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Frequently asked questions
Can I take Celecoxib with Ginger?
MediHelp rates the interaction as minor. Celecoxib and Ginger have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginger may inhibit platelet aggregation at higher supplemental doses, which could theoretically add to NSAID-related bleeding. Evidence for clinically meaningful bleeding is weak.
How serious is the interaction between Celecoxib and Ginger?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; advise reporting bruising or bleeding, and avoid high-dose ginger supplements around surgery.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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