Drug interactions
Celecoxib + Ginkgo biloba
Severity: Moderate
Celecoxib and Ginkgo biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo inhibits platelet-activating factor and has been linked to case reports of bleeding. Combined with an NSAID, bleeding risk may be somewhat increased, although controlled data are inconsistent.
What this interaction means in plain words
Celecoxib and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effects on platelet function and GI mucosal injury.
What to do
Advise avoiding ginkgo while on celecoxib, especially with other antithrombotics, and stop it before surgery. Monitor for bleeding if combined.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Ginkgo biloba?
MediHelp rates the interaction as moderate. Celecoxib and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo inhibits platelet-activating factor and has been linked to case reports of bleeding. Combined with an NSAID, bleeding risk may be somewhat increased, although controlled data are inconsistent.
How serious is the interaction between Celecoxib and Ginkgo biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo while on celecoxib, especially with other antithrombotics, and stop it before surgery. Monitor for bleeding if combined.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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