Drug interactions
Celecoxib + Neomycin po
Severity: Minor
Celecoxib and Neomycin po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin is poorly absorbed, so systemic interaction is minimal. The reported effect of NSAIDs raising aminoglycoside levels relates mainly to parenteral aminoglycosides in preterm infants.
What this interaction means in plain words
Celecoxib and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical NSAID-reduced renal clearance of absorbed aminoglycoside.
What to do
No action is needed in most patients. Monitor renal function if the patient has renal impairment or bowel disease that increases neomycin absorption.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Neomycin po?
MediHelp rates the interaction as minor. Celecoxib and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin is poorly absorbed, so systemic interaction is minimal. The reported effect of NSAIDs raising aminoglycoside levels relates mainly to parenteral aminoglycosides in preterm infants.
How serious is the interaction between Celecoxib and Neomycin po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed in most patients. Monitor renal function if the patient has renal impairment or bowel disease that increases neomycin absorption.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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