Drug interactions
Celecoxib + Nettle
Severity: Minor
Celecoxib and Nettle: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nettle has been proposed to affect coagulation and blood pressure, but evidence of a real interaction with celecoxib is weak. The direction and magnitude of any effect are unclear.
What this interaction means in plain words
Celecoxib and Nettle have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; theoretical effects of nettle on coagulation and diuresis.
What to do
Ask patients about herbal use and monitor for unusual bleeding or changes in blood pressure, particularly if also on anticoagulants.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Nettle?
MediHelp rates the interaction as minor. Celecoxib and Nettle have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nettle has been proposed to affect coagulation and blood pressure, but evidence of a real interaction with celecoxib is weak. The direction and magnitude of any effect are unclear.
How serious is the interaction between Celecoxib and Nettle?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and monitor for unusual bleeding or changes in blood pressure, particularly if also on anticoagulants.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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