Drug interactions
Celecoxib + Telmisartan
Severity: Moderate
Celecoxib and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celecoxib can reduce the blood pressure lowering effect of telmisartan. In elderly, volume depleted or renally impaired patients the combination may cause acute kidney injury and raise serum potassium.
What this interaction means in plain words
Celecoxib and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Celecoxib belongs to Musculoskeletal; Telmisartan belongs to Cardiovascular.
Why it happens
NSAID inhibition of renal prostaglandins reduces renal perfusion and opposes angiotensin receptor blockade.
What to do
Monitor blood pressure, serum creatinine and potassium after starting or changing therapy and ensure adequate hydration. Use the lowest effective celecoxib dose for the shortest time.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Celecoxib with Telmisartan?
MediHelp rates the interaction as moderate. Celecoxib and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celecoxib can reduce the blood pressure lowering effect of telmisartan. In elderly, volume depleted or renally impaired patients the combination may cause acute kidney injury and raise serum potassium.
How serious is the interaction between Celecoxib and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum creatinine and potassium after starting or changing therapy and ensure adequate hydration. Use the lowest effective celecoxib dose for the shortest time.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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