Drug interactions
Celecoxib + Temocillin
Severity: Minor
Celecoxib and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are highly protein bound and eliminated in part by the kidney, so competition is theoretically possible. In practice a clinically meaningful change in either drug is unlikely, though NSAIDs may impair renal function and slow temocillin elimination.
What this interaction means in plain words
Celecoxib and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical protein-binding displacement and reduced renal clearance if NSAID-related renal impairment occurs.
What to do
No dose change is usually required. Monitor renal function in patients with impaired kidney function or at risk of dehydration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Temocillin?
MediHelp rates the interaction as minor. Celecoxib and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are highly protein bound and eliminated in part by the kidney, so competition is theoretically possible. In practice a clinically meaningful change in either drug is unlikely, though NSAIDs may impair renal function and slow temocillin elimination.
How serious is the interaction between Celecoxib and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually required. Monitor renal function in patients with impaired kidney function or at risk of dehydration.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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