Drug interactions
Celecoxib + Ticarcillin
Severity: Minor
Celecoxib and Ticarcillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are protein bound and renally eliminated, so interaction is theoretically possible. Ticarcillin can also impair platelet function, and NSAID-related renal impairment could reduce penicillin clearance, but significant effects are uncommon.
What this interaction means in plain words
Celecoxib and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical protein-binding competition, reduced renal clearance with NSAID nephrotoxicity, and possible additive platelet effects.
What to do
No routine adjustment is needed. Monitor renal function and watch for bleeding in high-dose or renally impaired patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Ticarcillin?
MediHelp rates the interaction as minor. Celecoxib and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are protein bound and renally eliminated, so interaction is theoretically possible. Ticarcillin can also impair platelet function, and NSAID-related renal impairment could reduce penicillin clearance, but significant effects are uncommon.
How serious is the interaction between Celecoxib and Ticarcillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor renal function and watch for bleeding in high-dose or renally impaired patients.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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