Drug interactions
Celiprolol + Enalapril-hydrochlorothiazide
Severity: Minor
Celiprolol and Enalapril-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide can reduce celiprolol exposure, and the drugs have additive blood-pressure lowering. The net effect is usually modest.
What this interaction means in plain words
Celiprolol and Enalapril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Reduced gastrointestinal absorption or altered transport of celiprolol, plus additive antihypertensive effects.
What to do
Monitor blood pressure and heart rate and adjust celiprolol dose if control is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enalapril-hydrochlorothiazide
- Aliskiren + Enalapril-hydrochlorothiazide Contraindicated
- Dofetilide + Enalapril-hydrochlorothiazide Contraindicated
- Enalapril-hydrochlorothiazide + Protein a column Contraindicated
- Enalapril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Amifostine + Enalapril-hydrochlorothiazide Major
- Amiloride + Enalapril-hydrochlorothiazide Major
Frequently asked questions
Can I take Celiprolol with Enalapril-hydrochlorothiazide?
MediHelp rates the interaction as minor. Celiprolol and Enalapril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide can reduce celiprolol exposure, and the drugs have additive blood-pressure lowering. The net effect is usually modest.
How serious is the interaction between Celiprolol and Enalapril-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and adjust celiprolol dose if control is inadequate.
What other medicines interact with Enalapril-hydrochlorothiazide?
MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.
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