Drug interactions
Celiprolol + Fosinopril-hydrochlorothiazide
Severity: Minor
Celiprolol and Fosinopril-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide may reduce oral celiprolol absorption and exposure, possibly weakening its effect. The two agents are also both antihypertensive, so blood pressure effects are additive overall.
What this interaction means in plain words
Celiprolol and Fosinopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Reduced intestinal absorption of celiprolol, possibly via transporter effects, with additive pharmacodynamic blood pressure lowering.
What to do
Monitor blood pressure and heart rate and adjust celiprolol dose if control is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fosinopril-hydrochlorothiazide
- Aliskiren + Fosinopril-hydrochlorothiazide Contraindicated
- Dofetilide + Fosinopril-hydrochlorothiazide Contraindicated
- Fosinopril-hydrochlorothiazide + Protein a column Contraindicated
- Fosinopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aldesleukin + Fosinopril-hydrochlorothiazide Major
- Amifostine + Fosinopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Celiprolol with Fosinopril-hydrochlorothiazide?
MediHelp rates the interaction as minor. Celiprolol and Fosinopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide may reduce oral celiprolol absorption and exposure, possibly weakening its effect. The two agents are also both antihypertensive, so blood pressure effects are additive overall.
How serious is the interaction between Celiprolol and Fosinopril-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and adjust celiprolol dose if control is inadequate.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
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