Drug interactions
Celiprolol + Ipratropium-salbutamol
Severity: Moderate
Celiprolol and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a beta-blocker with beta-1 selectivity and weak partial beta-2 agonist activity, and it can blunt the bronchodilator effect of salbutamol. The risk is greatest in patients with asthma or reactive airways and at higher celiprolol doses.
What this interaction means in plain words
Celiprolol and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism of beta-2 receptor mediated bronchodilation.
What to do
Monitor respiratory status and the response to salbutamol, and avoid celiprolol in patients with significant asthma where possible. Consider an alternative antihypertensive if bronchospasm occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Celiprolol and Ipratropium-salbutamol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ipratropium-salbutamol
Frequently asked questions
Can I take Celiprolol with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Celiprolol and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker with beta-1 selectivity and weak partial beta-2 agonist activity, and it can blunt the bronchodilator effect of salbutamol. The risk is greatest in patients with asthma or reactive airways and at higher celiprolol doses.
How serious is the interaction between Celiprolol and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory status and the response to salbutamol, and avoid celiprolol in patients with significant asthma where possible. Consider an alternative antihypertensive if bronchospasm occurs.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
