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Drug interactions

Celiprolol + Isoproterenol

Severity: Moderate

Celiprolol and Isoproterenol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Celiprolol is a beta-blocker that opposes the effects of isoproterenol at beta receptors, so the cardiac and bronchodilator response to isoproterenol may be reduced.

What this interaction means in plain words

Celiprolol and Isoproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Competitive beta-adrenergic receptor antagonism by celiprolol against isoproterenol.

What to do

Monitor heart rate, blood pressure and respiratory status; higher isoproterenol doses may be needed. Be alert for bronchospasm in susceptible patients.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Celiprolol with Isoproterenol?

MediHelp rates the interaction as moderate. Celiprolol and Isoproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker that opposes the effects of isoproterenol at beta receptors, so the cardiac and bronchodilator response to isoproterenol may be reduced.

How serious is the interaction between Celiprolol and Isoproterenol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and respiratory status; higher isoproterenol doses may be needed. Be alert for bronchospasm in susceptible patients.

What other medicines interact with Isoproterenol?

MediHelp also lists interactions of Isoproterenol with, for example, Adrenaline-articaine, Bisoprolol, Budesonide-formoterol. The full list is on the Isoproterenol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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