Drug interactions
Celiprolol + Nicardipine
Severity: Moderate
Celiprolol and Nicardipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents lower blood pressure, so combining them can cause additive hypotension. Beta-blockers combined with dihydropyridines are commonly used, but dosing needs care.
What this interaction means in plain words
Celiprolol and Nicardipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antihypertensive effect through vasodilation and beta-blockade.
What to do
Monitor blood pressure and heart rate and titrate doses gradually. Reduce one agent if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nicardipine
Frequently asked questions
Can I take Celiprolol with Nicardipine?
MediHelp rates the interaction as moderate. Celiprolol and Nicardipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents lower blood pressure, so combining them can cause additive hypotension. Beta-blockers combined with dihydropyridines are commonly used, but dosing needs care.
How serious is the interaction between Celiprolol and Nicardipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and titrate doses gradually. Reduce one agent if symptomatic hypotension occurs.
What other medicines interact with Nicardipine?
MediHelp also lists interactions of Nicardipine with, for example, Amifostine, Amlodipine-olmesartan-hydrochlorothiazide, Betrixaban. The full list is on the Nicardipine page.
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