Drug interactions
Celiprolol + Nimodipine
Severity: Moderate
Celiprolol and Nimodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, so combining them can cause additive hypotension. Beta-blockade may also blunt the reflex tachycardia from nimodipine. This matters most in patients with subarachnoid hemorrhage, where cerebral perfusion pressure is important.
What this interaction means in plain words
Celiprolol and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic hypotensive effects of calcium channel blockade and beta-blockade.
What to do
Monitor blood pressure and heart rate closely. Divide the nimodipine dose or reduce it if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Celiprolol with Nimodipine?
MediHelp rates the interaction as moderate. Celiprolol and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, so combining them can cause additive hypotension. Beta-blockade may also blunt the reflex tachycardia from nimodipine. This matters most in patients with subarachnoid hemorrhage, where cerebral perfusion pressure is important.
How serious is the interaction between Celiprolol and Nimodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate closely. Divide the nimodipine dose or reduce it if hypotension develops.
What other medicines interact with Nimodipine?
MediHelp also lists interactions of Nimodipine with, for example, Apalutamide, Carbamazepine, Ceritinib. The full list is on the Nimodipine page.
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