Drug interactions
Certolizumab pegol + Poliovirus vaccine inactivated
Severity: Minor
Certolizumab pegol and Poliovirus vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Certolizumab may lower the antibody response to inactivated poliovirus vaccine, although the vaccine is safe to give.
What this interaction means in plain words
Certolizumab pegol and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF-alpha blockade attenuates the immune response to vaccine antigens.
What to do
Complete inactivated vaccinations before starting certolizumab when possible. Do not withhold the vaccine if therapy is already underway.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contraindicated
- Bcg intravesical live + Certolizumab pegol Contraindicated
- Bcg vaccine live + Certolizumab pegol Contraindicated
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine live Contraindicated
Frequently asked questions
Can I take Certolizumab pegol with Poliovirus vaccine inactivated?
MediHelp rates the interaction as minor. Certolizumab pegol and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Certolizumab may lower the antibody response to inactivated poliovirus vaccine, although the vaccine is safe to give.
How serious is the interaction between Certolizumab pegol and Poliovirus vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete inactivated vaccinations before starting certolizumab when possible. Do not withhold the vaccine if therapy is already underway.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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