Drug interactions
Chasteberry + Ziprasidone
Severity: Minor
Chasteberry and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chasteberry has dopaminergic activity and could in theory oppose the dopamine-blocking effects of ziprasidone. No clinically significant interaction has been well documented.
What this interaction means in plain words
Chasteberry and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic antagonism at dopamine D2 receptors.
What to do
No routine action is needed. Watch for loss of antipsychotic effect if chasteberry is started.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Frequently asked questions
Can I take Chasteberry with Ziprasidone?
MediHelp rates the interaction as minor. Chasteberry and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chasteberry has dopaminergic activity and could in theory oppose the dopamine-blocking effects of ziprasidone. No clinically significant interaction has been well documented.
How serious is the interaction between Chasteberry and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Watch for loss of antipsychotic effect if chasteberry is started.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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