Drug interactions
Chloral hydrate + Salbutamol
Severity: Minor
Chloral hydrate and Salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chloral hydrate is a sedative-hypnotic and salbutamol is mildly stimulant, with no established clinically meaningful interaction. Chloral hydrate may sensitise the myocardium to catecholamines, a theoretical concern.
What this interaction means in plain words
Chloral hydrate and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chloral hydrate belongs to Central Nervous System; Salbutamol belongs to Respiratory.
Why it happens
No established mechanism; opposing CNS effects and a theoretical catecholamine arrhythmia sensitisation.
What to do
No routine action; monitor heart rate if high-dose salbutamol is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salbutamol
Other interactions of Chloral hydrate
- Calcium / magnesium / potassium / sodium oxybates + Chloral hydrate Contraindicated
- Chloral hydrate + Sodium oxybate Contraindicated
- Alfentanil + Chloral hydrate Major
- Alprazolam + Chloral hydrate Major
- Amobarbital + Chloral hydrate Major
- Belladonna and opium + Chloral hydrate Major
Frequently asked questions
Can I take Chloral hydrate with Salbutamol?
MediHelp rates the interaction as minor. Chloral hydrate and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chloral hydrate is a sedative-hypnotic and salbutamol is mildly stimulant, with no established clinically meaningful interaction. Chloral hydrate may sensitise the myocardium to catecholamines, a theoretical concern.
How serious is the interaction between Chloral hydrate and Salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; monitor heart rate if high-dose salbutamol is used.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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