Drug interactions
Chlordiazepoxide + Levetiracetam
Severity: Moderate
Chlordiazepoxide and Levetiracetam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence, dizziness and coordination problems, so combined use may increase drowsiness. Levetiracetam can also cause mood and behavioural changes that may be harder to recognize with sedation.
What this interaction means in plain words
Chlordiazepoxide and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlordiazepoxide belongs to Central Nervous System; Levetiracetam belongs to Central Nervous System.
Why it happens
Additive CNS depression; no significant pharmacokinetic interaction is expected.
What to do
Counsel about driving and machinery and monitor for excess sedation when starting or increasing either drug. Adjust doses if drowsiness limits function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlordiazepoxide
Other interactions of Levetiracetam
Frequently asked questions
Can I take Chlordiazepoxide with Levetiracetam?
MediHelp rates the interaction as moderate. Chlordiazepoxide and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause somnolence, dizziness and coordination problems, so combined use may increase drowsiness. Levetiracetam can also cause mood and behavioural changes that may be harder to recognize with sedation.
How serious is the interaction between Chlordiazepoxide and Levetiracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel about driving and machinery and monitor for excess sedation when starting or increasing either drug. Adjust doses if drowsiness limits function.
What other medicines interact with Chlordiazepoxide?
MediHelp also lists interactions of Chlordiazepoxide with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide page.
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