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Drug interactions

Chlordiazepoxide + Terbinafine

Severity: Minor

Chlordiazepoxide and Terbinafine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Chlordiazepoxide is metabolized mainly by oxidation and glucuronidation, not clinically by CYP2D6. A relevant interaction with terbinafine is not expected.

What this interaction means in plain words

Chlordiazepoxide and Terbinafine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Chlordiazepoxide belongs to Central Nervous System; Terbinafine belongs to Anti Fungals.

Evidence level: Low

Why it happens

No established mechanism; CYP2D6 is not a major pathway for chlordiazepoxide.

What to do

No specific action is needed beyond usual monitoring of sedation.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chlordiazepoxide with Terbinafine?

MediHelp rates the interaction as minor. Chlordiazepoxide and Terbinafine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chlordiazepoxide is metabolized mainly by oxidation and glucuronidation, not clinically by CYP2D6. A relevant interaction with terbinafine is not expected.

How serious is the interaction between Chlordiazepoxide and Terbinafine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond usual monitoring of sedation.

What other medicines interact with Terbinafine?

MediHelp also lists interactions of Terbinafine with, for example, Thioridazine, Desipramine, Eliglustat. The full list is on the Terbinafine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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