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Drug interactions

Chlordiazepoxide-clidinium + Sage

Severity: Minor

Chlordiazepoxide-clidinium and Sage: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Some sage preparations are traditionally described as having sedative properties, which could add to the sedation caused by chlordiazepoxide. The clinical significance is uncertain and based largely on theory. Any effect would most likely be modest at dietary amounts.

What this interaction means in plain words

Chlordiazepoxide-clidinium and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive CNS depressant effect; the mechanism for sage is not firmly established.

What to do

Counsel patients taking medicinal sage products or teas in large amounts to watch for increased drowsiness. Advise caution with driving and avoid concurrent alcohol.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Chlordiazepoxide-clidinium with Sage?

MediHelp rates the interaction as minor. Chlordiazepoxide-clidinium and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Some sage preparations are traditionally described as having sedative properties, which could add to the sedation caused by chlordiazepoxide. The clinical significance is uncertain and based largely on theory. Any effect would most likely be modest at dietary amounts.

How serious is the interaction between Chlordiazepoxide-clidinium and Sage?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients taking medicinal sage products or teas in large amounts to watch for increased drowsiness. Advise caution with driving and avoid concurrent alcohol.

What other medicines interact with Chlordiazepoxide-clidinium?

MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.

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