Drug interactions
Chlorpheniramine + Danazol
Severity: Minor
Chlorpheniramine and Danazol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol inhibits CYP3A4 and may raise chlorpheniramine levels, which could increase sedation and anticholinergic effects. The effect is probably small.
What this interaction means in plain words
Chlorpheniramine and Danazol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Danazol inhibition of CYP3A4 reduces chlorpheniramine metabolism.
What to do
Monitor for increased drowsiness or anticholinergic effects and lower the chlorpheniramine dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlorpheniramine
Frequently asked questions
Can I take Chlorpheniramine with Danazol?
MediHelp rates the interaction as minor. Chlorpheniramine and Danazol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol inhibits CYP3A4 and may raise chlorpheniramine levels, which could increase sedation and anticholinergic effects. The effect is probably small.
How serious is the interaction between Chlorpheniramine and Danazol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased drowsiness or anticholinergic effects and lower the chlorpheniramine dose if needed.
What other medicines interact with Chlorpheniramine?
MediHelp also lists interactions of Chlorpheniramine with, for example, Belladonna and opium, Benzhydrocodone / acetaminophen, Brexanolone. The full list is on the Chlorpheniramine page.
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