Drug interactions
Chlorpheniramine + Motherwort
Severity: Minor
Chlorpheniramine and Motherwort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort has traditional sedative properties and may add to the drowsiness caused by chlorpheniramine. Evidence is limited and based largely on theoretical additive effects.
What this interaction means in plain words
Chlorpheniramine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive CNS depressant effects; mechanism is not well established.
What to do
Advise patients to watch for excess drowsiness and avoid driving if affected. Consider stopping the herbal product if sedation is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Chlorpheniramine and Motherwort, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Chlorpheniramine
Frequently asked questions
Can I take Chlorpheniramine with Motherwort?
MediHelp rates the interaction as minor. Chlorpheniramine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort has traditional sedative properties and may add to the drowsiness caused by chlorpheniramine. Evidence is limited and based largely on theoretical additive effects.
How serious is the interaction between Chlorpheniramine and Motherwort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and avoid driving if affected. Consider stopping the herbal product if sedation is troublesome.
What other medicines interact with Chlorpheniramine?
MediHelp also lists interactions of Chlorpheniramine with, for example, Belladonna and opium, Benzhydrocodone / acetaminophen, Brexanolone. The full list is on the Chlorpheniramine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
