Drug interactions
Chlorpropamide + Cyclosporin
Severity: Minor
Chlorpropamide and Cyclosporin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
There are reports of altered sulfonylurea effect and cyclosporine exposure with concurrent use, but the data are limited. Changes in glycemic control or cyclosporine levels are possible.
What this interaction means in plain words
Chlorpropamide and Cyclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlorpropamide belongs to Endocrine; Cyclosporin belongs to Miscellaneous.
Why it happens
The mechanism is not established.
What to do
Monitor blood glucose and cyclosporine trough levels when either drug is started, stopped or adjusted.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Chlorpropamide and Cyclosporin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Other interactions of Chlorpropamide
Frequently asked questions
Can I take Chlorpropamide with Cyclosporin?
MediHelp rates the interaction as minor. Chlorpropamide and Cyclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. There are reports of altered sulfonylurea effect and cyclosporine exposure with concurrent use, but the data are limited. Changes in glycemic control or cyclosporine levels are possible.
How serious is the interaction between Chlorpropamide and Cyclosporin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and cyclosporine trough levels when either drug is started, stopped or adjusted.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
