Drug interactions
Cholic acid + Colestipol
Severity: Moderate
Cholic acid and Colestipol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bile acid binding resins bind cholic acid in the gut and reduce its absorption. This can weaken the therapeutic effect of cholic acid in bile acid synthesis disorders.
What this interaction means in plain words
Cholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholic acid belongs to Gastrointestinal Tract; Colestipol belongs to Cardiovascular.
Why it happens
Colestipol adsorbs bile acids in the intestinal lumen, preventing their absorption.
What to do
Take cholic acid at least 1 hour before or 4 to 6 hours after colestipol. Monitor clinical and biochemical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cholic acid
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Cholic acid with Colestipol?
MediHelp rates the interaction as moderate. Cholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bile acid binding resins bind cholic acid in the gut and reduce its absorption. This can weaken the therapeutic effect of cholic acid in bile acid synthesis disorders.
How serious is the interaction between Cholic acid and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take cholic acid at least 1 hour before or 4 to 6 hours after colestipol. Monitor clinical and biochemical response.
What other medicines interact with Cholic acid?
MediHelp also lists interactions of Cholic acid with, for example, Bosentan, Cholestyramine, Glibenclamide. The full list is on the Cholic acid page.
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