Drug interactions
Chromium + Hydrocortisone
Severity: Minor
Chromium and Hydrocortisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may increase urinary chromium loss, and chromium supplementation has been reported to influence glucose handling. The clinical consequence is unclear and likely small.
What this interaction means in plain words
Chromium and Hydrocortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chromium belongs to Gastrointestinal Tract; Hydrocortisone belongs to Endocrine.
Why it happens
Proposed increase in renal chromium excretion by glucocorticoids; the mechanism is not well established.
What to do
No specific action is required; monitor blood glucose if the patient is diabetic and taking both.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrocortisone
- Hydrocortisone + Mifepristone Contraindicated
- Hydrocortisone + Poliovirus vaccine live oral trivalent Contraindicated
- Hydrocortisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Hydrocortisone Major
- Aldesleukin + Hydrocortisone Major
- Aspirin + Hydrocortisone Major
Other interactions of Chromium
- Chromium + Omadacycline Moderate
- Chromium + Sarecycline Moderate
- Acarbose + Chromium Minor
- Acetylsalicylic acid + Chromium Minor
- Alogliptin-metformin + Chromium Minor
- Alogliptin-pioglitazone + Chromium Minor
Frequently asked questions
Can I take Chromium with Hydrocortisone?
MediHelp rates the interaction as minor. Chromium and Hydrocortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may increase urinary chromium loss, and chromium supplementation has been reported to influence glucose handling. The clinical consequence is unclear and likely small.
How serious is the interaction between Chromium and Hydrocortisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is required; monitor blood glucose if the patient is diabetic and taking both.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Smallpox vaccine live. The full list is on the Hydrocortisone page.
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