Drug interactions
Chromium + Omadacycline
Severity: Moderate
Chromium and Omadacycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral chromium supplements may bind omadacycline in the gut and reduce its absorption. This could lower antibiotic exposure and risk treatment failure.
What this interaction means in plain words
Chromium and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chromium belongs to Gastrointestinal Tract; Omadacycline belongs to Anti Bacterial.
Why it happens
Chelation of the tetracycline by polyvalent metal cations in the gastrointestinal tract reduces absorption.
What to do
Take omadacycline at least 4 hours before or after oral chromium-containing supplements, or hold the supplement during therapy. Monitor clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chromium
Other interactions of Omadacycline
- Acitretin + Omadacycline Contraindicated
- Isotretinoin + Omadacycline Major
- Omadacycline + Tretinoin Major
- Aluminum hydroxide + Omadacycline Moderate
- Amoxicillin-clavulanic acid + Omadacycline Moderate
- Amoxicillin + Omadacycline Moderate
Frequently asked questions
Can I take Chromium with Omadacycline?
MediHelp rates the interaction as moderate. Chromium and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral chromium supplements may bind omadacycline in the gut and reduce its absorption. This could lower antibiotic exposure and risk treatment failure.
How serious is the interaction between Chromium and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take omadacycline at least 4 hours before or after oral chromium-containing supplements, or hold the supplement during therapy. Monitor clinical response to the antibiotic.
What other medicines interact with Chromium?
MediHelp also lists interactions of Chromium with, for example, Sarecycline, Acarbose, Acetylsalicylic acid. The full list is on the Chromium page.
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