Drug interactions
Chromium + Sarecycline
Severity: Moderate
Chromium and Sarecycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral chromium supplements may bind sarecycline in the gut and reduce its absorption. This could reduce efficacy in acne treatment.
What this interaction means in plain words
Chromium and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chromium belongs to Gastrointestinal Tract; Sarecycline belongs to Anti Bacterial.
Why it happens
Chelation of the tetracycline by polyvalent metal cations in the gastrointestinal tract reduces absorption.
What to do
Separate sarecycline from chromium-containing supplements by at least 2 to 3 hours, or avoid the supplement during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chromium
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Chromium with Sarecycline?
MediHelp rates the interaction as moderate. Chromium and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral chromium supplements may bind sarecycline in the gut and reduce its absorption. This could reduce efficacy in acne treatment.
How serious is the interaction between Chromium and Sarecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline from chromium-containing supplements by at least 2 to 3 hours, or avoid the supplement during therapy.
What other medicines interact with Chromium?
MediHelp also lists interactions of Chromium with, for example, Omadacycline, Acarbose, Acetylsalicylic acid. The full list is on the Chromium page.
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