Drug interactions
Cilostazol + Cortisone
Severity: Minor
Cilostazol and Cortisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cortisone may modestly induce CYP3A4, which could lower cilostazol exposure and reduce its benefit for intermittent claudication. The effect is likely small and varies between patients.
What this interaction means in plain words
Cilostazol and Cortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible glucocorticoid-mediated induction of CYP3A4, increasing cilostazol metabolism.
What to do
No dose change is normally needed; reassess claudication symptom response if systemic cortisone is given long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cilostazol
Frequently asked questions
Can I take Cilostazol with Cortisone?
MediHelp rates the interaction as minor. Cilostazol and Cortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cortisone may modestly induce CYP3A4, which could lower cilostazol exposure and reduce its benefit for intermittent claudication. The effect is likely small and varies between patients.
How serious is the interaction between Cilostazol and Cortisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is normally needed; reassess claudication symptom response if systemic cortisone is given long term.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.
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