Skip to content

Drug interactions

Cilostazol + Devil's claw

Severity: Minor

Cilostazol and Devil's claw: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Devil's claw has been reported to have antiplatelet activity and may add to the antiplatelet effect of cilostazol. Evidence is conflicting and the clinical significance is uncertain.

What this interaction means in plain words

Cilostazol and Devil's claw have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive inhibition of platelet function; the herbal effect is not well established.

What to do

Ask about herbal use and advise against routine use. Monitor for bruising or bleeding if continued.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Cilostazol and Devil's claw, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Cilostazol with Devil's claw?

MediHelp rates the interaction as minor. Cilostazol and Devil's claw have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has been reported to have antiplatelet activity and may add to the antiplatelet effect of cilostazol. Evidence is conflicting and the clinical significance is uncertain.

How serious is the interaction between Cilostazol and Devil's claw?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use and advise against routine use. Monitor for bruising or bleeding if continued.

What other medicines interact with Cilostazol?

MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in