Drug interactions
Cilostazol + Icosapent
Severity: Minor
Cilostazol and Icosapent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icosapent ethyl may modestly prolong bleeding time, which could add to the antiplatelet effect of cilostazol. Clinically important bleeding is uncommon.
What this interaction means in plain words
Cilostazol and Icosapent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antiplatelet effects of omega-3 fatty acid and PDE3 inhibition.
What to do
No dose change required; watch for bruising and bleeding, particularly with other antithrombotic drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cilostazol and Icosapent, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cilostazol
Frequently asked questions
Can I take Cilostazol with Icosapent?
MediHelp rates the interaction as minor. Cilostazol and Icosapent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Icosapent ethyl may modestly prolong bleeding time, which could add to the antiplatelet effect of cilostazol. Clinically important bleeding is uncommon.
How serious is the interaction between Cilostazol and Icosapent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change required; watch for bruising and bleeding, particularly with other antithrombotic drugs.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
