Drug interactions
Cilostazol + Lumefantrine
Severity: Minor
Cilostazol and Lumefantrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lumefantrine has weak CYP3A4 induction potential, so cilostazol levels could fall slightly. Because artemether-lumefantrine is short-course, any effect is likely brief and minor.
What this interaction means in plain words
Cilostazol and Lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak CYP3A4 induction increasing cilostazol metabolism.
What to do
No adjustment is usually needed; reassess symptoms if a longer course is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cilostazol
Frequently asked questions
Can I take Cilostazol with Lumefantrine?
MediHelp rates the interaction as minor. Cilostazol and Lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lumefantrine has weak CYP3A4 induction potential, so cilostazol levels could fall slightly. Because artemether-lumefantrine is short-course, any effect is likely brief and minor.
How serious is the interaction between Cilostazol and Lumefantrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is usually needed; reassess symptoms if a longer course is used.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.
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