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Drug interactions

Cilostazol + Miconazole vaginal

Severity: Minor

Cilostazol and Miconazole vaginal: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Vaginal miconazole is absorbed to a small degree but can inhibit CYP3A4 and CYP2C9; it is mainly a concern with warfarin. An effect on cilostazol is possible but is likely small.

What this interaction means in plain words

Cilostazol and Miconazole vaginal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Limited systemic absorption of miconazole with possible CYP3A4 inhibition.

What to do

No routine adjustment; monitor for cilostazol adverse effects during prolonged or repeated courses.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cilostazol with Miconazole vaginal?

MediHelp rates the interaction as minor. Cilostazol and Miconazole vaginal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vaginal miconazole is absorbed to a small degree but can inhibit CYP3A4 and CYP2C9; it is mainly a concern with warfarin. An effect on cilostazol is possible but is likely small.

How serious is the interaction between Cilostazol and Miconazole vaginal?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment; monitor for cilostazol adverse effects during prolonged or repeated courses.

What other medicines interact with Cilostazol?

MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.

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