Drug interactions
Cimetidine + Devil's claw
Severity: Minor
Cimetidine and Devil's claw: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw may stimulate gastric acid secretion and could theoretically oppose the effect of acid-suppressing drugs. No clinical evidence confirms this.
What this interaction means in plain words
Cimetidine and Devil's claw have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic opposition between an acid-stimulating herb and an H2 antagonist.
What to do
Advise patients with peptic ulcer or reflux disease to avoid devil's claw, and monitor symptom control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cimetidine and Devil's claw, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cimetidine
- Cimetidine + Dofetilide Contraindicated
- Cimetidine + Fezolinetant Contraindicated
- Alfentanil + Cimetidine Major
- Atazanavir + Cimetidine Major
- Carmustine + Cimetidine Major
- Cimetidine + Citalopram Major
Frequently asked questions
Can I take Cimetidine with Devil's claw?
MediHelp rates the interaction as minor. Cimetidine and Devil's claw have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw may stimulate gastric acid secretion and could theoretically oppose the effect of acid-suppressing drugs. No clinical evidence confirms this.
How serious is the interaction between Cimetidine and Devil's claw?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients with peptic ulcer or reflux disease to avoid devil's claw, and monitor symptom control.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
