Drug interactions
Cimetidine + Green tea
Severity: Minor
Cimetidine and Green tea: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Green tea contains caffeine, and cimetidine slows caffeine clearance, which may heighten stimulant effects. With normal tea intake the impact is small.
What this interaction means in plain words
Cimetidine and Green tea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cimetidine belongs to Gastrointestinal Tract; Green tea belongs to Gastrointestinal Tract.
Why it happens
Cimetidine inhibits CYP1A2-mediated caffeine metabolism.
What to do
Advise limiting green tea or caffeine-containing products if jitteriness, palpitations or insomnia occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cimetidine
- Cimetidine + Dofetilide Contraindicated
- Cimetidine + Fezolinetant Contraindicated
- Alfentanil + Cimetidine Major
- Atazanavir + Cimetidine Major
- Carmustine + Cimetidine Major
- Cimetidine + Citalopram Major
Other interactions of Green tea
- Adenosine + Green tea Moderate
- Benzphetamine + Green tea Moderate
- Bortezomib + Green tea Moderate
- Dextroamphetamine + Green tea Moderate
- Diethylpropion + Green tea Moderate
- Ephedrine + Green tea Moderate
Frequently asked questions
Can I take Cimetidine with Green tea?
MediHelp rates the interaction as minor. Cimetidine and Green tea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Green tea contains caffeine, and cimetidine slows caffeine clearance, which may heighten stimulant effects. With normal tea intake the impact is small.
How serious is the interaction between Cimetidine and Green tea?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise limiting green tea or caffeine-containing products if jitteriness, palpitations or insomnia occur.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
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