Drug interactions
Cinnamon + Indomethacin
Severity: Minor
Cinnamon and Indomethacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cinnamon, especially cassia varieties containing coumarin, may have mild antiplatelet activity. With indomethacin, a theoretical increase in bleeding tendency exists, but clinical evidence is lacking.
What this interaction means in plain words
Cinnamon and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak additive antiplatelet effect; the mechanism is not well established.
What to do
No routine action is needed with dietary amounts. Ask patients using concentrated cinnamon supplements to report unusual bruising or bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Frequently asked questions
Can I take Cinnamon with Indomethacin?
MediHelp rates the interaction as minor. Cinnamon and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnamon, especially cassia varieties containing coumarin, may have mild antiplatelet activity. With indomethacin, a theoretical increase in bleeding tendency exists, but clinical evidence is lacking.
How serious is the interaction between Cinnamon and Indomethacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed with dietary amounts. Ask patients using concentrated cinnamon supplements to report unusual bruising or bleeding.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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