Drug interactions
Cinnamon + Sulindac
Severity: Minor
Cinnamon and Sulindac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cinnamon, especially cassia varieties, contains coumarin and may have mild antiplatelet activity. With sulindac, there is a theoretical rise in bleeding risk at supplement doses, while culinary amounts are unlikely to matter.
What this interaction means in plain words
Cinnamon and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive effect on hemostasis from coumarin content and possible antiplatelet activity of cinnamon.
What to do
No action needed for dietary amounts. Advise patients taking concentrated cinnamon supplements to report unusual bruising or bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Frequently asked questions
Can I take Cinnamon with Sulindac?
MediHelp rates the interaction as minor. Cinnamon and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnamon, especially cassia varieties, contains coumarin and may have mild antiplatelet activity. With sulindac, there is a theoretical rise in bleeding risk at supplement doses, while culinary amounts are unlikely to matter.
How serious is the interaction between Cinnamon and Sulindac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed for dietary amounts. Advise patients taking concentrated cinnamon supplements to report unusual bruising or bleeding.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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